Some of my favorite cartoons are:
1. Ed, Edd n EddyIt's been my favorite North American cartoon of all time for many years. The humor is something that has always clicked with me. I often find myself quoting the show, especially around my sister, who grew up watching the show with me as well. It's a stupid, but entertaining show at the same time.
2. Teen TitansNote: This does not include Teen Titans Go! That show is pretty mediocre in my opinion.Teen Titans has a good balance of humor and serious plot-driven storylines. The anime-style animation is a plus as well; I think it fits the style of the show. The voice acting is pretty good, though it falters in some places. Overall, a solid show through and through.
3. Avatar - The Last AirbenderI pretty much like Avatar for the same reasons I like Teen Titans, though the voice acting is definitely better in Avatar. Great characters and character development as well.
4. The Legend of KorraIt's a nice follow-up to Avatar. The second season was a little disappointing, but still entertaining for what it was. Again, great characters, good humor, and solid animation. Of all the cartoons still airing currently, Korra is definitely my favorite.
5. Jackie Chan AdventuresI mainly like this show because of the character, Uncle, but the other characters can be funny as well. I always looked forward to watching this show on Saturday mornings on Kids' WB.
6. Samurai JackA surprisingly deep show for a cartoon on Cartoon Network. Though there was humor at times, this show was mainly serious most of the time. It had a good plot though: it's about a samurai who gets transported to the future (beyond present day) against his will and how he survives in a futuristic world with robots and other obstacles he has to overcome. Throughout the series, he looks for a way to get back home to his time period. I haven't seen every episode, but the ones I did see were very good. Highly recommended.